Dynamic light scattering (also known as photon correlation spectroscopy or quasi-elastic light scattering) is a technique in physics that can be used to determine the size distribution profile of small particles in suspension or polymers in solution. It can also be used to probe the behavior of complex fluids such as concentrated polymer solutions. [cited from wiki]
This site also have some useful notes on this techniques:
The well established theory for PCS is only valid for light being scattered once. Any contribution of multiple scattered light leads to erroneous PCS results and misinterpretations. As a consequence, PCS requires highly diluted suspensions in order to avoid multiple scattering. The low concentration of particles makes this method sensitive to impurities in the liquid. So usually very pure liquids and a clean room environment have to be used for the preparation and the operation. For further details please refer to ISO 33321 (1996).
In contrast to PCS, Photon Cross-correlation Spectroscopy (PCCS) as offered by Sympatec can be used for the measurement of particle size and stability of nanoparticles in high concentrated opaque supensions and emulsions, as multiple scattering is completely eliminated.
So this technique can also be used in optical trapped nanoparticles to determine the particle size or dynamics, see the following article:
This site also have some useful notes on this techniques:
The well established theory for PCS is only valid for light being scattered once. Any contribution of multiple scattered light leads to erroneous PCS results and misinterpretations. As a consequence, PCS requires highly diluted suspensions in order to avoid multiple scattering. The low concentration of particles makes this method sensitive to impurities in the liquid. So usually very pure liquids and a clean room environment have to be used for the preparation and the operation. For further details please refer to ISO 33321 (1996).
In contrast to PCS, Photon Cross-correlation Spectroscopy (PCCS) as offered by Sympatec can be used for the measurement of particle size and stability of nanoparticles in high concentrated opaque supensions and emulsions, as multiple scattering is completely eliminated.
So this technique can also be used in optical trapped nanoparticles to determine the particle size or dynamics, see the following article:
- “Localized dynamic light scattering: probing single particle dynamics at the nanoscale,” Phys. Rev. Lett.79, 154–157 (1997).
- “Localized dynamic light scattering: a new approach to dynamic measurements in optical microscopy,” Biophys. J. 74, 1541–1548 (1998)
- "Photon Correlation Spectroscopy in Particle Sizing", Encyclopedia of Analytical Chemistry, R.A. Meyers (Ed.), pp. 5469–5485, John Wiley & Sons Ltd, Chichester, 2000